The worshipers and the monk Alexandros: The Praying Ones are those who appeared in the Antiochian dioceses in the last quarter of the fourth century. They adhered to prayer, especially doxology, and repeated it constantly because they claimed that every person has a devil that can only be expelled by prayer. They practiced asceticism, fasting, staying up late, and working, and they adhered to sleep and lived on alms. They claimed that through prayer and detachment from money they were strongly united with God. Hence, they considered themselves angels, prophets, leaders, and Christs.

The most famous of these worshippers is the monk Alexander. He began his monastic life in northern Syria and the island. Sometimes he would travel preaching the Gospel and sometimes he would gather monks to live with them in a permanent residence. He visited Antioch in the early fifth century, but suspicions surrounded him and he was expelled from it. He went to Constantinople, where he became the source of problems during the reign of Atticus, its bishop.